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AR(Acetyl-K631) rabbit pAb
  • AR(Acetyl-K631) rabbit pAb
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更新時間:2025-03-10 21:00:08

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SourceRabbitApplicationsWB,ELISAReactivityHuman:K631,Mouse:K610,Rat:K613DilutionWB:1:500-1:2000
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human:K631,Mouse:K610,Rat:K613

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of AR(Acetyl-K631), It doesn't reacte with total protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized Acetyl peptide derived from human AR. at AA range: K631

  • Uniprot No

    P10275

  • Alternative names

    Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    androgen receptor(AR) Homo sapiens The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoform

  • Other

    AR DHTR NR3C4, AR, Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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