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ABCG2 rabbit pAb
  • ABCG2 rabbit pAb
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更新時間:2025-03-10 21:00:08

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SourceRabbitApplicationsIF,WB,IHC,ELISAReactivityHumanDilutionIF:1:50-200WB:1:500-1:2000
  • Source

    Rabbit

  • Applications

    IF,WB,IHC,ELISA

  • Reactivity

    Human

  • Dilution

    IF: 1:50-200 WB: 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    ABCG2 Polyclonal Antibody detects endogenous levels of ABCG2 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from the Internal region of human ABCG2. AA range:461-510

  • Uniprot No

    Q9UNQ0

  • Alternative names

    ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    ATP binding cassette subfamily G member 2 (Junior blood group)(ABCG2) Homo sapiens The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

  • Other

    ABCG2, ATP-binding cassette sub-family G member 2; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338

  • Mol.Wt (Da)

    72314

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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