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Acetyl p53 (K386) rabbit pAb
  • Acetyl p53 (K386) rabbit pAb
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更新時間:2025-03-10 21:00:08

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SourceRabbitApplicationsIHC,IF,WB,ELISAReactivityHumanDilutionWB1:500-2000IHC:1:100-1:300
  • Source

    Rabbit

  • Applications

    IHC,IF,WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB 1:500-2000 IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Acetyl-p53 (K386) Polyclonal Antibody detects endogenous levels of p53 protein only when acetylated at K386.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human p53 around the acetylated site of Lys386. AA range:344-393

  • Uniprot No

    P04637

  • Alternative names

    TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],

  • Other

    TP53, Cellular tumor antigen p53

  • Mol.Wt (Da)

    43653

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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