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Rabbit
WB,IHC,ELISA
Human,Mouse
WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
-20°C/1 year
ACK Polyclonal Antibody detects endogenous levels of ACK protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
The antiserum was produced against synthesized peptide derived from human ACK1. AA range:250-299
Q07912
TNK2; ACK1; Activated CDC42 kinase 1; ACK-1; Tyrosine kinase non-receptor protein 2
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
tyrosine kinase non receptor 2(TNK2) Homo sapiens This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],
TNK2, Activated CDC42 kinase 1; Tyrosine kinase non-receptor protein 2
114327
1 mg/ml
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