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Caspase-8 rabbit pAb
  • Caspase-8 rabbit pAb
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更新時(shí)間:2025-03-10 21:00:08

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SourceRabbitApplicationsWB
  • Source

    Rabbit

  • Applications

    WB,IHC

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:1000-2000 IHC: 1:50-100

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Caspase-8 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Recombinant Protein of Caspase-8

  • Uniprot No

    Q14790

  • Alternative names

    CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH

  • Form

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caspase 8(CASP8) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alt

  • Other

    CASP8, Caspase-8

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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