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Source

Rabbit

Applications

WB,IHC,IF,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

14-3-3 β Polyclonal Antibody detects endogenous levels of 14-3-3 β protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human 14-3-3 beta. AA range:41-90

Uniprot No

P31946

Alternative names

YWHAB; 14-3-3 protein beta/alpha; Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta(YWHAB) Homo sapiens This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008],

Other

YWHAB, 14-3-3 protein beta/alpha

Mol.Wt (Da)

28082

Concentration

1 mg/ml