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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous levels of AGTR1.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from human AGTR1 Polyclonal

Uniprot No

P30556

Alternative names

Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

angiotensin II receptor type 1(AGTR1) Homo sapiens Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012],

Other

AGTR1 AGTR1A AGTR1B AT2R1 AT2R1B, Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)

Concentration

1 mg/ml