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Source

Rabbit

Applications

WB,IHC,IF,ELISA

Reactivity

Human,Mouse

Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

AIFL Polyclonal Antibody detects endogenous levels of AIFL protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59

Uniprot No

Q96NN9

Alternative names

AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid glａnd and tongue (at protein level).,

Other

AIFM3, Apoptosis-inducing factor 3

Mol.Wt (Da)

66791

Concentration

1 mg/ml