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目錄:上海貝博生物科技有限公司>>Primary Antibodies>> ALS2 rabbit pAb

ALS2 rabbit pAb
  • ALS2 rabbit pAb
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更新時(shí)間:2025-05-26 21:29:53瀏覽次數(shù):148評價(jià)

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SourceRabbitApplicationsWB
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB 1:500-2000 ELISA 1:5000-20000

  • Storage

    -20°C/1 year

  • Specificity

    ALS2 Polyclonal Antibody detects endogenous levels of protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from human protein . at AA range: 390-470

  • Uniprot No

    Q96Q42

  • Form

    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    ALS2, alsin Rho guanine nucleotide exchange factor(ALS2) Homo sapiens The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],

  • Other

    ALS2 ALS2CR6 KIAA1563, Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)

  • Concentration

    1 mg/ml

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