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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Storage

-20°C/1 year

Specificity

Caldesmon Polyclonal Antibody detects endogenous levels of Caldesmon

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human CALD1. AA range:1-50

Uniprot No

Q05682

Alternative names

Caldesmon (CDM)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

Other

CALD1, Caldesmon

Mol.Wt (Da)

93231

Concentration

1 mg/ml