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Source

Rabbit

Applications

IHC,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB 1:500-2000 ,IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Phospho-Catenin-α1 (S641) Polyclonal Antibody detects endogenous levels of Catenin-α1 protein only when phosphorylated at S641.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human Catenin-alpha1 around the phosphorylation site of Ser641. AA range:607-656

Uniprot No

P35221

Alternative names

CTNNA1; Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

catenin alpha 1(CTNNA1) Homo sapiens This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016],

Other

CTNNA1, Catenin alpha-1

Mol.Wt (Da)

100071

Concentration

1 mg/ml