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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Storage

-20°C/1 year

Specificity

CCR8 Polyclonal Antibody detects endogenous levels of protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from human protein . at AA range: 250-330

Uniprot No

P51685

Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

C-C motif chemokine receptor 8(CCR8) Homo sapiens This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008],

Other

CCR8 CKRL1 CMKBR8 CMKBRL2, C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (CC chemokine receptor CHEMR1) (CMKBRL2) (Chemokine receptor-like 1) (CKR-L1) (GPR-CY6) (GPRCY6) (TER1) (CD antigen CDw198)

Concentration

1 mg/ml