 | 重慶市華雅干細胞技術有限公司 |
15021010459
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NT-3 神經生長因子 StemRD NT-010/050/250
| 參考價 | 面議 |
- 型號 NT-010/050/250
- 品牌 StemRD/美國
- 廠商性質 代理商
- 所在地 重慶市
更新時間：2025-02-12 13:28:00瀏覽次數：1277
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產品信息
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors that also include NGF, BDNF and NT-4/5. These secreted neurotrophins are processed proteolytically from a disulfide-containing precursor. The mature and bio-active form of NT-3 is a noncovalentlylinked homodimer of two 13.6kDa identical subunits. StemRD's NT-3is made in human 293 cells which renders natural dimerization and human-specific post-translational modifications. We purified this product through a series of chromatography including HPLC to near homogeneity.
Purity:
Greater than 95% by SDS-PAGE under reducing conditions and visualized by silver staining.
Biological Activity
The activity was determined by using a NFAT luciferase reporter gene assay in 293 cells cotransfected with TrkC receptor (Wang, et al., Cellular Assays for High-Throughput Screening for Modulators of Trk Receptor Tyrosine Kinases. Curr Chem Genomics. 2008; 1: 27–33). The EC50 ranges from0.5 - 5.0 ng/ml
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